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I am also Vit B12 deficient and also have ulcerative colitis. I have been having B12 injections for years but have never felt any different as a result. Yes, they are a rather scratchy injection so they are briefly painful but it wears off immediately so don’t be put off.

Edited to add that I’ve just re-read post from poster above me who says that they make her arm a bit sore for a couple of hours afterwards but I have never found that. Just shows we are all different and will react to things in different ways. Either that or I’m so used to being poked, prodded and otherwise mauled around on a regular basis that I no longer notice things