Forums Ask for advice B12 deficiency Reply To: B12 deficiency March 20, 2018 at 1:49 pm #368 kath 6 Posts I am B12 deficient and will need continual injections, for me it was discovered after being diagnosed with Ulcerative Colitis. After my booster injections I felt so much better! Symptoms for me were, fatigue, pins and needles/ numbness in my hands and brain fog. I only really noticed the symptoms after I was treated and they went away , amazing what you put up with when things happen gradually… Didn’t know about the jumpiness, I am the jumpiest person ever ! I’m due my next injection next Monday and feel a bit crap again, so definitely B12 related, I’m going to ask if I can have slightly more frequent injections . Injections are just into the muscle so not awful, but can make your arm a bit sore for a couple of hours, try not to worry (easy said than done I know, I also hate injections!).